There's also a comparison, which I like EVEN better, that Lana is Green K (as above), therefore his weakness, and Lois is the Sun, therefore his strength. There are lots of visual examples of this, but the one that really comes to mind in at the end of Pandora when Clark returns to Watchtower, steps into the sun and replies to Ollie's question of why he's so happy: "The sun is shining, Lois is going to be alright."
Ooh, I like this imagery! And now that I think of it, I can recall several scenes with this sort of juxtaposition... but I also think there is something to the Green K/ Red K. How often is Lois wearing red, and when she suggests with a sort of *wink,wink*, for Clark to try a little Wild Cherry -- obviously that's about her.

Perhaps the Red K/passion association is why Clark never encountered Lois when the Red K went in the opposite direction, when he became 'the bad boy every girl dreams about -- in her nightmares,' as Chloe had put it.
Season 10 reference-->
Still, would have been interesting to see Clark on Red K, in destructive mode with Lois in on the secret -- curious how she would have handled it. Oh well... guess that means more fodder for fanfic.