Well, I see it this way:
1) Lois won't be completely out of the picture, she just won't start out as Clark's wife. Which means that the whole getting closer will start all over again - and that's way more interesting to me than the married stuff.
2) In the comics, they had quite a few issues regarding LnC's marriage that were still unresolved, among them the absolute biological incompatibility between humans and Kryptonians, problems of a sexual nature (never without protection, or it might prove fatal for Lois, and never with Clark playing an active role because he could all too easily break her in half - after all, soul-mates were from the show, not the comics!)
3) Most important DC characters (including not only absolutely all superheroes, but also characters like Lois!) will get a complete make-over, and the traits that define them will be fleshed out over time. And it would defeat the purpose of starting with a clean slate if you start LnC as a married couple.
And who knows? Maybe DC saw the light and will make Clark the real person, and Superman the disguise...
