My favorite couple that didn't make the list is probably Sam and Diane from Cheers. Now there was a rocky relationship that came and went and came and went and came and finally went for the last time. The scene in the fifth season finale where Diane left to write her book and Sam's realization that she wouldn't be back made for a very poignant moment. The look on his face when he said, "Have a good life," was very sad.
