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Originally posted by Shadow:
We actually don't know a lot about it, so it's definitely one of this season's mysteries. I think someone died, or...insert a similar car-related tragedy...I'm tempted to say they're going to start explaining a few things in our next episode.
Actually, they explained a bit about it in one of the episodes, the one after they first show the car crash, I think. It's when they showed why Susan and Mike split up. Susan and Mike were in one car, a mother and child were in another car. Susan and Mike survived, the other car didn't. And Susan couldn't handle it.

Edit: I see what Labby posted now, and it's right. It's not speculation, but what was said in one of the episodes. laugh

"You need me. You wouldn't be much of a hero without a villain. And you do love being the hero, don't you. The cheering children, the swooning women, you love it so much, it's made you my most reliable accomplice." -- Lex Luthor to Superman, Question Authority, Justice League Unlimited